Department of Biochemistry and Metabolic Science, Graduate School of Medicine, Akita
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2025/04/07 A paper was published (Nat Metab 2025).



Pre-fertilization-origin preservation of brown fat-mediated energy expenditure in humans.
Nature Metabolism (2025) DOI:10.1038/s42255-025-01249-2

 We showed that people who were conceived (pregnant) during the cold season have more activated brown fat, which produces heat, consume more energy, and are less likely to develop obesity as adults. The research shows that influence of the living environment of the parent generation is transmitted to their children, helping them acquire a heat-producing constitution and prevent lifestyle-related diseases, and is expected to lead to new methods of preventing lifestyle-related diseases.
 This is a join research project with Prof. Sakai and Assoc. Prof. Yoneshiro of Tohoku University, Prof. Emeritus Saito of Hokkaido University, Prof. Hamaoka and Assist. Prof. Fuse of Tokyo Medical University, Lecturer Matsushita of Tenshi University, and Prof. Nakamura of the University of Tokyo.

Tohoku University Press Release (Japanese only)
The University of Tokyo Press Release (Japanese only)


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