DEFINITION OF PAIN AND DISTRESS AND REPORTING REQUIREMENTS
Proceedings of the Workshop held june 22, 2000
National Research Council
EXPLANATION OF CATEGORIES
The descriptions we may include in a policy will not necessarily mimic or restate what the regulations state because the purpose of a policy is to provide clarification of the existing regulation. We hope that the following explanations and examples (among many) of the various categories will clarify these categories.
Description : Testing, teaching, or experiments involving no pain, distress, or use of pain-relieving medications. Again, recognize that pain or distress must be more than slight or momentary to be, by definition, a painful procedure.
Example : Collection of a blood sample from a peripheral vein not resulting in pain or distress. The animal remains calm throughout.
Description : Testing, teaching, or experiments involving pain or distress for which appropriate analgesic, anesthetic, or tranquilizing drugs are used.
Examples : (1) Use of an anesthetic agent to prevent pain or distress associated with intercardiac blood collection or perhaps any number of other types of procedures. (2) Use of a therapeutic agent to remedy an intentionally induced disease process. It would be a bit of a leap from where we are now, since current regulations recognize only anesthetics, analgesics, and tranquilizers or other pain-relieving medications as a means to appropriately classify procedures in Column D.
Description: Teaching, testing, or experiments involving pain or distress for which the use of appropriate anesthetic, analgesics, or tranquilizing drugs would have adversely affected the procedure's results or the interpretation.
Examples : (1) Collection of an intercardiac blood sample without the use of pain-relieving medications. (2) Presence of an experimentally induced disease process that causes pain or distress that is not relieved by the use of pain-relieving medications .