- Frank JA, Imai Y, Slutsky AS, “Pathogenesis of ventilator-induced lung injury” Physiological Basis of Ventilatory Support 2009 (Marcel Dekker Inc.)
- Singer D, Camargo SM, Huggel K, Romeo E, Danilczyk U, Kuba K, Chesnov S, Caron MG, Penninger JM, Verrey F: Orphan Transporter SLC6A18 Is Renal Neutral Amino Acid Transporter B0AT3. J Biol Chem. 2009 Jul 24;284(30):19953-60.
- Kishi Y, Kuba K, Nakamura T, Wen J, Suzuki Y, Mizuno S, Nukiwa T, Matsumoto K, Nakamura T.: Systemic NK4 gene therapy inhibits tumor growth and metastasis of melanoma and lung carcinoma in syngeneic mouse tumor models. Cancer Sci. 2009 Jul;100(7):1351-8.
- Oudit GY, Imai Y, Kuba K, Scholey JW, Penninger JM: The role of ACE2 in pulmonary diseases--relevance for the nephrologist. Nephrol Dial Transplant. 2009 May;24(5):1362-5.
- Camargo SM, Singer D, Makrides V, Huggel K, Pos KM, Wagner CA, Kuba K, Danilczyk U, Skovby F, Kleta R, Penninger JM, Verrey F: Tissue-specific amino acid transporter partners ACE2 and Collectrin differentially interact with Hartnup mutations. Gastroenterology. 2009 Mar;136(3):872-82.
- Imai Y, Kuba K, Neely GG, Yaghubian-Malhami R, Perkmann T, van Loo G, Ermolaeva M, Veldhuizen R, Leung YH, Wang H, Liu H, Sun Y, Pasparakis M, Kopf M, Mech C, Bavari S, Peiris JS, Slutsky AS, Akira S, Hultqvist M, Holmdahl R, Nicholls J, Jiang C, Binder CJ, Penninger JM*. Identification of oxidative stress and toll like receptor 4 signaling as a key pathway of acute lung injury. Cell. 2008, 18;133(2):235-49.
- Imai Y, Kuba K, Penninger JM. The discovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice. Exp Physiol. 2008, 93(5):543-8
- Kuba K, Zhang L, Imai Y, Arab S, Chen M, Maekawa Y, Leschnik M, Leibbrandt A, Markovic M, Schwaighofer J, Beetz N, Musialek R, Neely GG, Komnenovic V, Kolm U, Metzler B, Ricci R, Hara H, Meixner A, Nghiem M, Chen X, Dawood F, Wong KM, Sarao R, Cukerman E, Kimura A, Hein L, Thalhammer J, Liu PP, Penninger JM Impaired Heart Contractility in Apelin Gene–Deficient Mice Associated With Aging and Pressure Overload. Circulation Research. 2007, 101:32-42.
- Imai Y, Kuba K, and Josef M. Penninger. Angiotensin converting enzyme 2 (ACE2) in acute respiratory distress syndrome (ARDS) Cell Mol Life Sci. 2007, 64(15):2006-12.
- Imai Y, Kuba K, Penninger JM. Renin angiotensin system and acute respiratory distress syndrome (ARDS). Drug Discovery Today. 2006, 3:225-229.
- Kuba K, Imai Y, Kuba K, Penninger JM. ACE2 in lung diseases. Curr Opin Pharmacol. 2006, 6(3):271-6.
- Kuba K, Imai Y, Penninger JM. Lessons from SARS: control of acute lung failure by the SARS receptor ACE2. Journal of Molecular Medicine. 2006, 84(10):814-20.
- Imai Y, Slutsky AS, “Systemic effects of mechanical ventilation” Update in Intensive Care and Emergency Medicine 2006 (Springer-Verlang Inc.)
- Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, Yang P, Sarao R, Wada T, Leong-Poi H, Crackower MA, Fukamizu A, Hui CC, Hein L, Uhlig S, Slutsky AS, Jiang C, Penninger JM. Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature. 2005 Jul 7;436(7047):112-6.
- Kuba K, Imai Y, Rao S, Gao H, Guo F, Guan B, Huan Y, Yang P, Zhang Y, Deng W, Bao L, Zhang B, Liu G, Wang Z, Chappell M, Liu Y, Zheng D, Leibbrandt A, Wada T, Slutsky AS, Liu D, Qin C, Jiang C, Penninger JM. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med. 2005 Aug;11(8):875-9.
- Imai Y, Slutsky AS. High-frequency oscillatory ventilation and ventilator-induced lung injury. Crit Care Med. 2005 Mar;33(3 Suppl):S129-34.
- de Perrot M, Quadri SM, Imai Y, Keshavjee S. Independent ventilation of the graft and native lungs in vivo after rat lung transplantation. Ann Thorac Surg. 2005 Jun;79(6):2169-71.
- Goggel R, Winoto-Morbach S, Vielhaber G, Imai Y, Lindner K, Brade L, Brade H, Ehlers S, Slutsky AS, Schutze S, Gulbins E, Uhlig S. PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide. Nat Med. 2004 Feb;10(2):155-60.
- Martins S, de Perrot M, Imai Y, Yamane M, Quadri SM, Segall L, Dutly A, Sakiyama S, Chaparro A, Davidson BL, Waddell TK, Liu M, Keshavjee S. Transbronchial administration of adenoviral-mediated interleukin-10 gene to the donor improves function in a pig lung transplant model. Gene Ther. 2004 Dec;11(24):1786-96.
- Imai Y, Parodo J, Kajikawa O, de Perrot M, Fischer S, Edwards V, Cutz E, Liu M, Keshavjee S, Martin TR, Marshall JC, Ranieri VM, Slutsky AS. Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome. JAMA. 2003 Apr 23-30;289(16):2104-12.
- de Perrot M, Fischer S, Liu M, Imai Y, Martins S, Sakiyama S, Tabata T, Bai XH, Waddell TK, Davidson BL, Keshavjee S. Impact of human interleukin-10 on vector-induced inflammation and early graft function in rat lung transplantation. Am J Respir Cell Mol Biol. 2003 May;28(5):616-25.
- de Perrot M, Young K, Imai Y, Liu M, Waddell TK, Fischer S, Zhang L, Keshavjee S. Recipient T cells mediate reperfusion injury after lung transplantation in the rat. J Immunol. 2003 Nov 15;171(10):4995-5002.
- Fischer S, De Perrot M, Liu M, MacLean AA, Cardella JA, Imai Y, Suga M, Keshavjee S. Interleukin 10 gene transfection of donor lungs ameliorates posttransplant cell death by a switch from cellular necrosis to apoptosis. J Thorac Cardiovasc Surg. 2003 Oct;126(4):1174-80.
- Slutsky AS, Imai Y. Ventilator-induced lung injury, cytokines, PEEP, and mortality: implications for practice and for clinical trials. Intensive Care Med. 2003 Aug;29(8):1218-21.

