２００４年

Horie Y, Suzuki A (equal first and corresponding author), Kataoka Ei, Sasaki T, Hamada K, Junko Sasaki, MIzuno K, Hasegawa G, Kishimoto H, Iizuka M, Naito M, Enomoto K, Watanabe S, Mak TW, Nakano T
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
JOURNAL OF CLINICAL INVESTIGATION 113(12), 1774-1783, 2004
(私達のものが表紙を飾りました）

Suzuki A, Sasaki T, Mak TW, Nakano T
Functional analysis of the tumour suppressor gene PTEN in murine B cells and keratinocytes
BIOCHEMICAL JOURNAL (BIOCHEMICAL SOCIETY TRANSACTION), 32 (2), 362-365, 2004

Backman SA, Ghazarian D, So K, Sanchez O, Wagner KU, Hennighausen L, Suzuki A, Tsao MS, Chapman WB, Stambolic V, Mak TW.
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten.
PROC NATL ACAD SCI USA. 101(6), 1725-30, 2004

Nishita M, Yan W, Goto K, Tomizawa C, Suzuki A, Niwa R, Umekura T, Mizuno K
PI3-kinase-Medeated Activation of Cofilin Phosphatase Slingshot-1L Controls Inslin-induced Membrane Protrusion
JOURNAL OF BIOLOGICAL CHEMISTRY 279(8), 7193-7198, 2004

佐々木雄彦、水野克典、仲野徹、鈴木聡
PTENホスファターゼとその生体における機能
細胞工学、23(5), 556-561, 2004

岸本恕征、佐々木雄彦、仲野徹、鈴木聡
PI3Kキナーゼ関連遺伝子欠損と免疫異常
Molecular Medicine, 41(5), 58-63, 2004

河原崎哲、濱田浩一、松田幸久、佐々木雄彦、仲野徹、鈴木聡
ＰＴＥＮとアポトーシス
Biotherapy, 18(2), 151-160, 2004

濱田浩一、佐々木雄彦、仲野徹、鈴木聡　
血液細胞における癌抑制遺伝子PTEN
血液・腫瘍科, 48(2), 190-195, 2004

岸本恕征、改正恒康、佐々木雄彦、仲野徹、鈴木聡
ＰＴＥＮによるＢ細胞の分化と機能制御
臨床免疫　41(2), 121-127, 2004

堀江泰夫、佐々木雄彦、飯塚政弘、渡邊純夫、鈴木聡
炎症とアポトーシス
２１世紀の胃の炎症学　, 2004 in press

２００３年

Suzuki A, Kaisho T, Ohishi M, Yamaguchi MT, Tsubata T, Koni PA, Sasaki T, Mak TW, Nakano T
Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination
JOURNAL of EXPERIMANTAL MEDICINE 197(5), 657-667, 2003

Suzuki A, Itami S, Ohishi M, Yamaguchi MT, Hamada K, Inoue T, Komazawa N, Senoo H, Sasaki T, Takeda J, Manabe M, Mak TW, Nakano T
Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation
CANCER RESEARCH 63(3), 674-681, 2003
(私達のものが表紙を飾りました）

Kimura T, Suzuki A, Fujita Y, Yomogida Y, Lomeli H, Asada N, Ikeuchi M, Nagy A, Mak TW, Nakano T
Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production
DEVELOPMENT 130(8), 1691-1700, 2003

Kishimoto H, Hamada K, Saunders M, Sasaki T, Nakano T, Mak TW and Suzuki A
Physiological Functions of PTEN in Mouse Tissues~ Analysis of the tissue specific PTEN mutant mice ~
CELL STRUCTURE and FUNCTION 28(1), 11-21, 2003

井上多恵、真鍋求、板見智、佐々木雄彦、仲野徹、鈴木聡
がん抑制遺伝子ＰＴＥＮと皮膚疾患
日本皮膚科学会雑誌　113(1), 1641-1650, 2003

２００２年
Crackower MA, Oudit GY, Kozieradzki I, Sarao R, Sasaki T, Suzuki A, Sasaki JI, Sah R, Cheng HYM, Oliveira-dos-Santos AO, Benovic JL, Kahn CR, Izumo S, Steinberg SF, Backx PH, Penninger J
Regulation of heart muscle contractility by the PI3Kg-PTEN signaling pathway
CELL 110(6) 737-749, 2002

Tanigaki K, Han H, Yamamoto N, Tashiro K, Ikegawa M, Kuroda K, Suzuki A, Nakano T and Honjo T
Notch / RBP-J signaling is involved in cell fate determination of Marginal Zone B cells
NATURE IMMUNOLOGY 3(5), 443-50, 2002

Cheung AM, Hande MP, Jalali F, Tsao MS, Skinnider B, Hirao A, McPherson JP, Karaskova J, Suzuki A, Wakeham A, You-Ten A, Elia A, Squire J, Bristow R, Hakem R, Mak TW.
Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis.
CANCER RESEARCH 62(21), 6194-204, 2002

Itoh H, Komatsuda A, Ohtani H, Wakui H, Imai H, Sawada K, Otaka M, Ogura M, Suzuki A, Hamada F
Mammalian HSP60 is quickly sorted into the mitchondria under dehydration
EUROPEAN JOURNAL of BIOCHEMISTRY 269(23), 5931-5938, 2002

Matsumori M, Itoh H, Toyoshima I, Komatsuda A, Sawada K, Fukuda J, Tanaka T, Okubo A, Kinouchi H, Mizoi K., Hama T, Suzuki A, Hamada F, Shoji Y, Takada G
Characterization of the 105-kDa molecular chaperone: Identification, biochemical properties, and lozalization
EUROPEAN JOURNAL of BIOCHEMISTRY 269(22), 5632-5641, 2002

木村透、鈴木聡、仲野徹
始原生殖細胞から全能性細胞へ：テラトーマのEG細胞
細胞工学　21 (8), 836-83, 2002, 秀潤社

鈴木聡、山口麻奈絵、大石美奈子、仲野徹
癌抑制遺伝子PTENと自己寛容
Annual Review免疫2002, 201-207,中外医学社

佐々木雄彦、山崎正和、鈴木聡
PI3Kによる極性発生
細胞骨格と細胞運動，169-174，2002, シュプリンガー・フェアラーク社

Sasaki T, Suzuki A, Sasaki J, Penninger JM.
Phosphoinositide 3-kinases in immunity: lessons from knockout mice.
JOURNAL of BIOCHEMISTRY 131(4), 495-501, 2002

２００1年
Suzuki A, Yamaguchi MT, Ohteki T, Sasaki T, Kaisho T, KimuraY, Yoshida R, Wakeham A, Higuchi T, Fukumoto M, Tsubata T, Ohashi P, Koyasu S, Penninger JM, Nakano T and Mak TW
T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance
IMMUNITY 14(5), 523-534, 2001

Suzuki A, Nakano T
Development of Hematopoietic Cells from embryonic stem cells
INTERNATIONAL JOURNAL of HEMATOLOGY 73(1), 1-5, 2001

Backman SA, Stambolic V, Suzuki A, Haight J, Elia A, Pretorius J, Tsao MS, Shannon P, Bolon B, Ivy GO, Mak TW.
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease.
NATURE GENETICS 29(4), 396-403, 2001

Sasaki T, Wada T, Kishimoto H, Irie-Sasaki J, Matsumoto G, Goto T, Yao Z, Wakeham A, Mak TW, Suzuki A, Cho SK, Zuniga-Pflucker JC,
Oliveira-dos-Santos AJ, Katada T, Nishina H, Penninger JM.
The stress kinase mitogen-activated protein kinase kinase (MKK)7 is a negative regulator of antigen receptor and growth factor receptor-induced proliferation in hematopoietic cells.
JOURNAL of EXPERIMANTAL MEDICINE 194(6), 757-768, 2001

Higuchi, M., Masuyama, N., Fukui, Y., Suzuki, A. and Gotoh, Y.
Akt mediates Rac/Cdc42-Regulated Cell Motility in Growth Factor-Stimulated Cells and in Invasive PTEN-Knockout Cells.
CURRENT BIOLOGY 11(24), 1958-1962, 2001

佐々木雄彦、鈴木聡、佐々木純子、Josef M.Penninger
PI3キナーゼとPIホスファターゼの免疫応答、糖代謝、腫瘍形成における役割
蛋白質核酸酵素 46(12), 1820-1829, 2001

佐々木雄彦、鈴木聡
PI3Kによる細胞遊走の制御
医学のあゆみ199 (13)，871-875，2001, 医歯薬出版

山口麻奈絵、鈴木聡、仲野徹
トレランス形成におけるPTENの意義
臨床免疫 35(6), 675-682, 2001

鈴木聡、仲野徹
PTEN変異と自己免疫疾患
実験医学別冊‘免疫総集編2001’19(5), 688-693, 2001

鈴木聡、佐々木雄彦、仲野徹
癌抑制遺伝子PTENの機能解析ﾑ生化学的・生理学的な役割
実験医学別冊‘アポトーシス研究の新たな挑戦’19(13), 1713-1719, 2001

大石美奈子、仲野徹、鈴木聡
組織特異的なPTENの不活化とT細胞トレランスの破綻
Molecular Medicine臨時増刊号 免疫2002 38, 85-93, 2001

２０００年
Sasaki T, Sasaki JI, Horie Y,Bachmaier K, Fata JE, Li M, Suzuki A, Bouchard D, Ho A, Redston M, Gallinger S , Khokha R, Mak TW, Hawkins PT, Stephens L, Scherer SW, Tsao M, Penninger JM
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)K-gammma
NATURE 406(6798), 897-902, 2000

Sasaki T, Sasaki JI, Jones RG, Oliveira-dos-Santos AJ, Stanford WL, Bolon B, Wakeham A, Itie A, Bouchard D, Kozieradzki I, Joza N, Mak TW, Ohashi
PS, Suzuki A, Penninger JM
Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration.
SCIENCE 287(5455), 1040-1046, 2000

Stambolic V, Tsao MS, Macpherson D, Suzuki A, Chapman WB, Mak TW
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice.
CANCER RESEARCH 60(13), 3605-3611, 2000

１９９８年
Stambolic-V, Suzuki-A(equal first contributor), de la-Pompa JL, Brothers-GM, Mirtsos-C, Sasaki-T, Ruland-J, Penninger-JM, Siderovski-DP, Mak-TW
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN.
CELL 95(1), 29-39 , 1998

Suzuki-A, de la Pompa-JL, Stambolic-V, Elia-AJ, Sasaki-T, Barrantes-IB, Ho-A, Wakeham-A, ltie-A, Khoo-W, Fukumoto-M, Mak-TW
High cancer susceptibility and embryonic lethality associated with mutation of
the PTEN tumor suppressor gene in mice.
CURRENT BIOLOGY 8(21), 1169-78, 1998

Akira Suzuki and Tak Wah Mak: CD34. In 'The gene knockout facts Book'(A-H).
(ed)Tak Wah Mak, Josef Penninger, John Roder, Janet Rossant, Mary Saunders.
p 168- 170. Academic Press, San Diego, USA, 1998

Akira Suzuki and Tak Wah Mak: BRCA2. In 'The gene knockout facts Book'(A-H).
(ed)Tak Wah Mak, Josef Penninger, John Roder, Janet Rossant, Mary Saunders.
p 95- 96. Academic Press, San Diego, USA, 1998

１９９７年
Suzuki-A. de-la-Pompa-JL. Hakem-R. Elia-A. Yoshida-R. Mo-R. Nishina-H. Chuang-T. Wakeham-A. Itie-A. Koo-W. Billia-P. Ho-A. Fukumoto-M. Hui-CC. Mak-TW.
Brca2 is required for embryonic cellular proliferation in the mouse.
GENES AND DEVELOPMENT 11(10), 1242-52, 1997.
(私達のものが表紙を飾りました）

鈴木聡、須田年生：CD34. ノックアウトマウスデ-タブック、Molecular Medicine 34（臨時増刊号）92-93、1997

１９９６年
Suzuki-A. Andrew-DP. Gonzalo-JA. Fukumoto-M. Spellberg-J. Hashiyama-M. Takimoto-H. Gerwin-N. Webb-I. Molineux-G. Amakawa-R. Tada-Y. Wakeham-A. Brown-J. McNiece-I. Ley-K. Butcher-EC. Suda-T. Gutierrez-Ramos-JC. Mak-TW.
CD34-deficient mice have reduced eosinophil accumulation after allergen exposure and show a novel crossreactive 90-kD protein.
BLOOD 87(9), 3550-62, 1996.

Grossman-A. Mittruecker-HW. Nicholl-J. Suzuki-A. Chung-S. Antonio-L. Suggs-S. Sutherland-GR. Siderovski-DP. Mak-TW.
Cloning of human lymphocyte-specific interferon regulatory factor(hLSIRF/hIRF4) and mapping of the gene to 6p23-p25.
GENOMICS 37(2), 229-33, 1996.

鈴木聡、福本学、須田年生：CD34欠損マウス.　実験医学　14、1869-71、1996

１９９５年
Tsuyuoka-R. Takahashi-T. Suzuki-A. Sasaki-Y. Nakamura-K. Fukumoto-M. Ohmori-K. Ohno-Y. Nakao-K.
A newly established megakaryoblastic/erythroid cell line that differentiates to red cells in the presence of erythropoietin and produces platelet-like particles.
STEM CELLS 13(1), 54-64, 1995.

TAKAHASHI T, SUZUKI A.
LIVER-DAMAGE IN PATIENTS WITH CSF-PRODUCING TUMORS - REPLY
AMERICAN JOURNAL OF MEDICINE
98 (6): 601-602 JUN 1995

１９９４年
Suzuki-A. Takahashi-T. Okuno-Y. Tsuyuoka-R. Sasaki-Y. Fukumoto-M. Katakami-H. Kita-K. Shibuya-T.
Production of parathyroid hormone-related protein by cultured human myeloma cells.
AMERICAN JOURNAL OF HEMATOLOGY. 45(1), 88-90, 1994.

Tsuyuoka-R. Takahashi-T. Sasaki-Y. Taniguchi-Y. Fukumoto-M. Suzuki-A. Nakamura-K. Kobayashi-S. Kudo-T. Nakao-K.
Colony-stimulating factor-producing tumours: production of granulocyte colony-stimulating factor and interleukin-6 is secondary to interleukin-1 production.
EUROPEAN JOURNAL OF CANCER 30A(14), 2130-6, 1994.

１９９３年
Suzuki-A. Takahashi-T. Okuno-Y. Seko-S. Fukuda-Y. Nakamura-K. Fukumoto-M. Konaka-Y. Imura-H.
Liver damage in patients with colony-stimulating factor-producing tumors.
AMERICAN JOURNAL OF MEDICINE 94(2), 125-32, 1993.

Fukumoto-M. Suzuki-A. Inazawa-J. Yoshimura-T. Arao-S. Takahashi-T. Nomura-H. Hiai-H.
Chromosomal location and structure of amplicons in two human cell lines with coamplification of c-myc and Ki-ras oncogenes.
SOMATIC CELL AND MOLECULAR GENETICS 19(1), 21-8, 1993.

１９９２年
Suzuki-A. Takahashi-T. Nakamura-K. Tsuyuoka-R. Okuno-Y. Enomoto-T. Fukumoto-M. Imura-H.
Thrombocytosis in patients with tumors producing colony-stimulating factor.
BLOOD 80(8), 2052-9, 1992.

Suzuki-A. Takahashi-T. Okuno-Y. Tsuyuoka-R. Fukumoto-M. Nakamura-K. Imura-H.
IL-1 production as a regulator of G-CSF and IL-6 production in CSF-producing cell lines.
BRITISH JOURNAL OF CANCER 65(4), 515-8, 1992.

Takahashi-T. Nakamura-K. Nishikawa-S. Tsuyuoka-R. Suzuki-A. Murakami-M. Amenomori-M. Okuno-Y. Imura-H.
Interleukin-5 in eosinophilic gastroenteritis.
AMERICAN JOURNAL OF HEMATOLOGY 40(4), 295-8, 1992.

Okuno-Y. Takahashi-T. Suzuki-A. Fukumoto-M. Nakamura-K. Fukui-H. Koishihara-Y. Ohsugi-Y. Imura-H.
Acquisition of growth autonomy and tumorigenicity by an interleukin 6-dependent human myeloma cell line transfected with interleukin 6 cDNA.
EXPERIMENTAL HEMATOLOGY 20(4), 395-400, 1992.

高橋隆幸、鈴木聡、福本学、坂根剛：CSF産生腫瘍における肝障害.　日常診療と血液2、1090-93, 1992

１９９１年
Suzuki-A. Takahashi-T. Okuno-Y. Nakamura-K. Tashiro-H. Fukumoto-M. Konaka-Y. Imura-H.
Analysis of abnormal expression of g-csf gene in a novel tumor cell line (KHC 287) elaborating G-CSF, IL-1 and IL-6 with co-amplification of c-myc and c-ki-ras.
INTERNATIONAL JOURNAL OF CANCER 48(3), 428-33, 1991.

Suzuki-A. Takahashi-T. Taniguchi-A. Kotake-C. Seo-T. Toda-T. Kobayashi-K. Tsukamoto-N. Fukumoto-M.
Pure red cell aplasia associated with non-Hodgkin's lymphoma and hemolytic anemia.
JAPANESE JOURNAL OF CLINICAL ONCOLOGY 21(5), 384-7, 1991.

Suzuki-A. Takahashi-T. Okuno-Y. Fukumoto-M. Fukui-H. Koishihara-Y. Ohsugi-Y. Ohno-Y. Imura-H.
Estimation of interleukin 6 production by reverse transcriptase-polymerase chain reaction in four human myeloma cell lines.
LEUKEMIA RESEARCH 15(11), 1043-50, 1991.

Nakamura-K. Takahashi-T. Tsuyuoka-R. Ueda-Y. Suzuki-A. Okuno-Y. Ihara-Y. Seko-S. Okada-T. Kumagai-N. Oyaizu-T, Nishimura-T
Identification of colony-stimulating factor activity in patients with malignant tumors associated with excessive leukocytosis.
JAPANESE JOURNAL OF CLINICAL ONCOLOGY 21(6), 395-9, 1991.

Takahashi-T. Suzuki-A. Ichiba-S. Okuno-Y. Sugiyama-H. Imura-H. Nakamura-K. Iho-S. Hoshino-T.
Effect of 1,25(OH)2D3 on normal human CFU-GM: target cells of the agent in the suppression of colony formation and induction of macrophage colonies.
INTERNATIONAL JOURNAL OF HEMATOLOGY 54(1), 57-63, 1991.

Okuno-Y. Takahashi-T. Suzuki-A. Ichiba-S. Nakamura-K. Okada-T. Okada-H. Imura-H.
In vitro growth pattern of myeloma cells in liquid suspension or semi-solid culture containing interleukin-6.
INTERNATIONAL JOURNAL OF HEMATOLOGY 54(1), 41-7, 1991.

Takahashi-T. Tsuyuoka-R. Ueda-Y. Suzuki-A. Ichiba-S. Okuno-Y. Nakamura-K. Imura-H.
Megakaryocyte potentiating activity of IL-1, IL-6 and GM-CSF as evaluated by their action on in vitro human megakaryocytic colonies.
BRITISH JOURNAL OF HAEMATOLOGY 78(4), 480-7, 1991.

Okuno-Y. Takahashi-T. Suzuki-A. Fukumoto-M. Nakamura-K. Imura-H.
Co-production of interleukin-1 and interleukin-6 in tumor cell lines elaborating colony-stimulating factors.
JAPANESE JOURNAL OF CANCER RESEARCH 82(8), 890-2, 1991.

Okuno-Y. Takahashi-T. Suzuki-A. Ichiba-S. Nakamura-K. Fukumoto-M. Okada-T. Okada-H. Imura-H.
Establishment and characterization of four myeloma cell lines which are responsive to interleukin-6 for their growth.
LEUKEMIA 5(7), 585-91, 1991.

１９９０年
Okuno-Y. Suzuki-A. Ichiba-S. Takahashi-T. Nakamura-K. Hitomi-K. Sasaki-R. Tada-K. Imura-H.
Establishment of an erythroid cell line (JK-1) that spontaneously differentiates to red cells.
CANCER 66(7), 1544-51, 1990.

Okuno-Y. Takahashi-T. Suzuki-A. Ichiba-S. Nakamura-K. Hitomi-K. Sasaki-R. Imura-H.
Expression of the erythropoietin receptor on a human myeloma cell line.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 170(3), 1128-34, 1990.