Division and Department

Department of Neurophysiology

Masahito KAWATANI, MD and PhD

A Greeting from the Professor

The major focus of our laboratory has been to define the organization of lumbosacral autonomic reflex pathways to the pelvic organs, and the mechanism of esophageal hypersensitivity by gastric acid reflux. We focus on: 1) the central mechanisms involved in viserosomatic integration, 2) change of afferent activity in chronic cystitis with visceral pain, 3) mechanism of ATP release from urotherial and/or esophageal epithelium cells, and 4) mechanism of spinal glutamate release caused by over-active bladder and/or esophageal hypersensitivity, and 5) signal transduction for relaxing corpus cavernosum.

Because of the rapidly increasing number of elderly people, over-active bladder, erectile dysfunction and gastroesophageal reflux disease have grown as targets for treatment. We are deeply involved in the mechanisms of these symptoms and in drug developments. We have long-term collaboration with several overseas universities as well as international drug companies. We regularly exchange staff and students for numerous successful projects. We have produced many seed ideas problem of these functions. We also have training programs for electrophysiology, neuro-pharmacology, urodynamics and molecular biology in basic science.


Masahito KAWATANI, MD and PhD

Assistant Professor:

Research Areas

  1. Autonomic neuroscience
  2. Pain
  3. Spinal cord and spinal cord injury
  4. Vesical function
  5. Visceral sensation
  6. Erectile and ejaculation dysfunction
  7. Urotherial cell function
  8. Esophageal hypersensitivity

Contact Information

Masaru YOSHIZUMI, PhD (yoshizumi@med.akita-u.ac.jp)
1-1-1 Hondo, Akita, 010-8543, Japan
Phone: +81-18-884-6073
Fax: +81-18-836-2605